Expert opinion from Nancy Anoruo
M.D. Faculty – Harvard Medical School · 5 years of experience · USA
Research suggests that depression is not simply a chemical imbalance. It doesn’t spring from simply having too much or too little of certain brain chemicals. Rather, there are many possible causes of depression, including faulty mood regulation by the brain, genetic vulnerability, and stressful life events. It’s believed that several of these forces interact to bring on depression. To be sure, chemicals are involved in this process, but it is not a simple matter of one chemical being too low and another too high. Rather, many chemicals are involved, working both inside and outside nerve cells. There are millions, even billions, of chemical reactions that make up the dynamic system that is responsible for your mood, perceptions, and how you experience life.
Expert opinion from Marcella Abunahman Pereira
Specialization in Clinical Cardiology · 12 years of experience · Brazil
The root causes of depression include family history, having other psychiatric disorder, being submitted to chronic stress, having chronic anxiety and hormonal dysfunctions, going through grief and loss, being overweight, having a sedentary lifestyle and unregulated diet, as well as having addictions (cigarettes, alcohol and illicit drugs).
Expert opinion from Sumit Kapoor
Doctor of Medicine (MBBS) · 9 years of experience · India
There is no single cause of depression. It can occur for a variety of reasons and has many different triggers. Common causes include stressful events, personality of the patient, family history, post partum, alcohol and drug abuse, chronic illness, underlying medical condition.
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